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Biology

Antiretrovirology at IgMin Research | Biology Group

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Antiretrovirology is an emerging and dynamic field at the intersection of virology, molecular biology, and pharmacology, focused on understanding and combating retroviruses such as HIV, HTLV, and other related pathogens. This specialized discipline explores the molecular mechanisms underlying retroviral replication, host-virus interactions, and the strategies these viruses employ to evade the immune system. By uncovering the complexities of retrovirus life cycles, antiretrovirology aims to provide new therapeutic targets and enhance treatment options for persistent viral infections. The field is critical in the development of antiviral drugs, immune-modulating therapies, and vaccines, especially for chronic infections like HIV/AIDS, where current treatments manage but do not fully eradicate the virus.

The research landscape of antiretrovirology is continually evolving, driven by advances in genomics, drug discovery, and molecular techniques. With the global health burden of retroviral diseases, innovative approaches such as gene therapy, CRISPR-Cas9-based strategies, and novel antiviral agents are being explored to halt or even cure retroviral infections. Furthermore, understanding viral resistance mechanisms, latency, and viral persistence remains pivotal to improving existing therapies and developing a comprehensive cure for retroviral infections. The growing integration of multidisciplinary approaches promises to revolutionize our understanding of retroviruses and create more effective and sustainable treatments for affected populations worldwide.

HIV reverse transcriptase inhibition Mechanisms of HIV latency and reactivation Strategies for curing HIV The role of long-acting injectable antiretrovirals HIV drug resistance and mutations HIV reservoir targeting and eradication strategies Gene editing technologies (CRISPR) for retroviral infections HIV immune evasion and immune modulation Advances in HIV vaccines Integrase inhibitors in HIV therapy Nanotechnology in retroviral drug delivery Host cell factors in retroviral replication Retrovirus-induced cancers Retroviral protease inhibitors HIV co-infections and management Molecular epidemiology of HIV Impact of gut microbiota on HIV progression Antiviral drug resistance in HIV therapy Advances in HIV diagnostics Role of viral latency in chronic HIV infections